Lung cancer - A slideshow
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Tuesday, November 23, 2010
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Friday, April 3, 2009
Child in ad shed real tears, producer admits
Visit msnbc.com for Breaking News, World News, and News about the Economy
A new anti-smoking ad that shows a frightened little boy has a lot of people talking. TODAY’s Matt Lauer talks to Fiona Sharkie, executive director of the anti-smoking group Quit Victoria, about why the group created the ad. Read more...
Saturday, March 28, 2009
ROMM Procedure describes Resection of Multiple Metastases lung cancer
A very important of lung cancer treatment clip, taken from Promise regional
Thursday, February 26, 2009
NicoBloc – Prepares you to stop smoking
Using NicoBloc to help you stop smoking by following the instructions that come with each pack to ensure you get the best out of the product.
Watch this complete instructional video on how to get the best from NicoBloc.
Monday, February 16, 2009
Paclitaxel - A new way to treat lung cancer
Paclitaxel is a monomer diterpenoid alkaloids compound extracted from taxaceae used in cancer chemotherapy to improve long-term survival in patients with advanced non-small cell lung cancer (NSCLC) as well as to treat patients with ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma.
TAXOL (paclitaxel) Injection is a clear, colorless, slightly yellow viscous solution which began to be translated into substantial improvements in Lung cancer patients care. Paclitaxel molecules shows a T-shaped or butterfly structure, being held together in stacks by intermolecular hydrogen bonds.
Taxol is supplied as a as an injectable solution intended for dilution with a suitable parenteral fluid prior to intravenous infusion.
Paclitaxel is a natural product with antitumor activity available in 30 mg (5 mL), 100 mg (16.7 mL), and 300 mg (50 mL) multidose vials.
Each mL of sterile nonpyrogenic solution contains 6 mg paclitaxel, 527 mg of purified Cremophor® EL* and 49.7% (v/v) dehydrated alcohol, USP.
When Taxol was developed commercially by Bristol-Myers Squibb (BMS) the generic name was changed to 'paclitaxel' and the BMS compound is sold under the trademark 'Taxol'. In this formulation paclitaxel is dissolved in Cremophor EL and ethanol, as a delivery agent.
A newer formulation, in which paclitaxel is bound to albumin, is sold under the trademark Abraxane.
What does Paclitaxel do in the Cell?
Paclitaxel interferes with the normal function of microtubule breakdown. Whereas drugs like colchicine cause the depolymerization of microtubules, paclitaxel arrests their function by having the opposite effect.
It hyper-stabilizes their structure, destroying the cell's ability to use its cytoskeleton in a flexible manner.
Source - Rxlist
Wikipedia
POXOLTM (Paclitaxel Injection) Read more...
Monday, February 9, 2009
Mesothelioma Causes, Symptoms, Diagnosis, Prognosis and Treatments
Mesothelioma is a form of cancer that is almost always caused by previous exposure to asbestos - A group of minerals that take the form of tiny fibers. In this disease, malignant cells develop in the mesothelium, a membrane that covers and protects most of the internal organs of the body.
Its most common site is the pleura - the pleural cavity is the body cavity that surrounds the lungs , but it may also occur in other places.
Most people who develop mesothelioma have worked on jobs where they inhaled asbestos particles, or they have been exposed to asbestos dust and fiber in other ways.Unlike lung cancer, Smoking does not appear to increase the risk of mesothelioma.
The symptoms of mesothelioma include shortness of breath and pain in the chest due to pleural effusion (fluid between the lung and the chest wall) or chest wall pain, and general symptoms such as weight loss, abdominal pain and swelling. The diagnosis may be suspected with chest X-ray and CT scan, and is confirmed with a biopsy (tissue sample) and microscopic examination.
The risk of asbestos-related disease increases with heavier exposure to asbestos and longer exposure time. However, some individuals with only brief exposures have developed mesothelioma. On the other hand, not all workers who are heavily exposed develop asbestos-related diseases.
How to confirm a diagnosis of mesothelioma?
Thoracoscopy - (inserting a tube with a camera into the chest) can be used to take biopsies. Thoracoscopy allows the doctor to look inside the chest and obtain tissue samples.
Peritoneoscopy - To obtain tissue for examination, the doctor makes a small opening in the abdomen and inserts a special instrument called a peritoneoscope into the abdominal cavity.
Despite treatment with chemotherapy, radiation therapy or sometimes surgery, the disease carries a poor prognosis. National Cancer Institute (NCI) is sponsoring clinical trials that are designed to find new treatments and better ways to use current treatments.
Sunday, February 8, 2009
Phase III Study Showed Tarceva in Combination With Avastin as First-Line Maintenance Therapy Improved Progression-Free Survival in Advanced Lung Cance
Genentech Inc. reports that a Phase III study (ATLAS) of Tarceva® (erlotinib) in combination with Avastin® (bevacizumab) as maintenance therapy following initial treatment with Avastin plus chemotherapy in advanced non-small cell lung cancer (NSCLC) met its primary endpoint.
According to the announcement, the study was stopped early on the recommendation of an independent data safety monitoring board after a pre-planned interim analysis showed that combining Tarceva and Avastin significantly extended the time patients lived without their disease advancing, as defined by progression-free survival (PFS), compared to Avastin plus placebo.
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